BROMORUTH 5% ORAL LIQUID

Bromhexine is a mucolytic drug used to decrease the viscosity of mucus in the airway, enhancing mucus clearance. Bromhexine thins airway secretions, improving breathing and discomfort associated with thick mucus in airways associated with a variety of respiratory conditions inflammation of the airways, increased mucus secretion and altered mucociliary clearance are the hallmarks of various diseases of the respiratory tract. Mucus clearance is necessary for lung health; bromhexine aids in mucus clearance by reducing the viscosity of mucus and activating the alliary epithelium. Considering absorption, its readily absorbed in the gastrointestinal tract at a rapid pH in this drug undergoes extensive first-pass effect in the range of 75-80 percent. The bioavailability is therefore reduced to approximately 22-27 percent. After a dose of bromhexine was administered during a pharmacokinetic study, approximately 97 percent of the radiolabeled dose was detected in the urine. It is used for respiratory tract infections like bronchitis, emphysema, silicosis, chronic lung inflammation, and bronchiectasis.