COLLISAL POWDER

DESCRIPTION: A WATER SOLUBLE POWDER FOR ORAL USE EACH GM COLISAL POWDER CONTAINS: COLISTIN SULPHATE鈥斺�斺�斺�斺�斺�斺��8,00,000 I.U DISCRIPTION: COLISTIN SULFATE IS AN ANTIBIOTIC POLYPEPTIDE WHICH POSSESSES ACTIVITY MAINLY AGAINST GRAM NEGATIVE BACTERIA AND IN VETERINARY MEDICINE IS USED ORALLY FOR THE TREATMENT OR PREVENTION OF ENTERITIS IN PRODUCTION ANIMALS. INDICATION: COLISTIN SHOWS A STRONG AND RAPID BACTERIAL ACTIVITY GRAM-NEGATIVE BACTERIA, ESPECIALLY SALMONELLA AND E.COIL. IT HAS BEEN OBSERVED THAT COLISTIN CAUSES MARKED FORMAL CHANGES IN THE BACTERIAL CELL WALL AND PASSES INTO THE CELL MEMBRANE AND FINALLY COMBINES WITH PHOSPHATIDE IN THE CELL MEMBRANE. IN THIS MECHANISM THE SURFACE TENSION IS DESCREASED AND MEMBERANE IS DESTROYED IT IS POORLY ABSORBED FROM THE GASTRO-INTESTINAL TRACT ORAL ADMINISTRATION, THUS OFFERING SPECIFIC ADVANTAGES IN THE TREATMENT AND CONTROL OF GASTRO-INTESTINAL INFECTION (COLIBACILLOSIS AND SALMONELLOSIS). Each gm contains:- Colistin Sulphate鈥︹�︹��800,000 IU. (Antibiotic).