Amidiofas Powder

PREVENTION AND TREATMENT OF COCCIDIOSIS AND BACTERIAL IN POULTRY. AMPROLIUM AMPROLIUM IS A COCCIDIOSTAT (ANTIPROTOZOAL) USED FOR THE TREATMENT AND PREVENTION OF COCCIDIOSIS IN CALVES, GOATS, SHEEP, CHICKENS (BROILERS AND BREEDERS) AND OTHER FOWL SUCH AS TURKEYS, WITH ACTIVITY AGAINST EIMERIA SPP,, ESPECIALLY EIMERIA TENELLA AND EIMERIA NECATRIX. LT IS A THIAMINE (VITAMIN B1) ANALOGUE AND ITS PHARMACOLOGICAL EFFECT RELIES ON COMPETITIVE INHIBITION OF THIAMINE UPTAKE. AMPROLIUM COMPETITIVELY INHIBITS THE ACTIVE TRANSPORT OF THIAMINE IN ISLOATED SECOND-GENERATION SCHIZONTS OT EIMERIA SPP. AND IN HOST INTESTINAL CELLS. UPON INGESTION OF AMPROLIUM, THE COCCIDIAN EXPERIENCE THIAMIN DEFICIENCY AND STARVE FROM MALNUTRITION. FURALTADONE. THIS NITROFURAN DERIVATIVE IS WELL ABSORBED AFTER ORAL ADMINISTRATION. ITS USE IS LARGELY IN TREATMENT OF POULTRY WHERE IT IS USED TO TREAT SALMONELLOSIS, COLI-BACILLOSIS, CAECAL COCCIDIOSIS, INFECTIOUS SYNOVITIS AND BLACKHEAD. TREATMENT IS FOR A MAXIMUM OF 5 DAYS, AFTER WHICH SIDE- EFFECTS, INCLUDING DEPRESSION OF APPETITE AND GROWTH, MAY BE SEEN.